Bio Performance Skin Filler Serums

$268.00
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Offers & Perks

Product Details

Web ID: 4562494

What It Is

A two-step system for visibly plump and firm skin. The revolutionary night and day system features Shiseido's proprietary Japanese Hyaluronic Acid. Rapidly diminish the signs of time with the breakthrough MolecuShift Technology, which first shrinks and then enlarges hyaluronic acid molecules to volumize the skin from within. In the evening, Infill Serum delivers shrunken hyaluronic acid molecules to be more effectively absorbed into skin. In the morning, Full Expansion Serum expands hyaluronic acid molecules back to their original size, leaving skin even more hydrated, plump and firm.
  • What It's For

    Normal, dry, very dry skin
  • What It Does

    - Visibly improves the look of wrinkles, fine lines and loss of firmness.
    - Helps skin gradually accumulate hyaluronic acid, a key component of skin, for long-lasting effects.
    - May be used in place of or in conjunction with injectable fillers to complement results.
    - Bottles, minus the cap, are 20% plant-derived and refills help reduce plastic waste by up to 74%.
  • Key Ingredients

    - Shrunken Bio-Hyaluronic Acid: Created through MolecuShift Technology, the world's first technology to successfully shrink the size of hyaluronic acid molecules and revert them back to their original size, without changing their structure. This allows the hyaluronic acid molecules to penetrate more easily without decreasing any of their advantages to plump and firm skin.
    - Red Clover Extract: Known to improve skin barrier function.
    - Chai Hu Extract: Known to promote collagen and hyaluronic acid production for firming benefits.
    - Cinnamon Extract: Helps optimize skin's natural purification process.
  • How To Use It

    - Apply before moisturizer. When using with other serums, apply Bio-Performance Skin Filler Serums as the last serum before your moisturizer.
    - In the evening, pump Infill Serum once onto fingertips and smooth evenly over face and neck.
    - In the morning, pump Full Expansion Serum once onto fingertips and smooth evenly over face and neck.
    - For Refills: Save the pumps and the caps from your original bottles. Insert the pumps into the refills, then close the caps.
  • Clinical Results

    - After one day of use, respondents who have tried medical beauty/cosmetics treatments said skin feels more volumized than ever and looks firm as if they had a medical treatment.*
    - Skin elasticity is improved, while wrinkles on cheek, under-eye area, nasolabial folds (smile lines) and crow's feet are less visible in 2 weeks.**
    *Based on 106 respondents who have tried medical beauty/cosmetics treatments.
    **Based on clinical tests with 31 women.
  • About The Brand

    Shiseido was the first cosmetics company to produce safe, high-quality bio-hyaluronic acid with two times more hydrating power and has continued to spend the last 40 years innovating and leading in hyaluronic acid research.
  • Features

    • Elle's Future of Beauty Award winner 2022
    • Items sold separately.
  • ingredients

    BIO-PERFORMANCE INFILL SERUM: Water (Aqua/Eau), Dipropylene Glycol, Alcohol Denat., Butylene Glycol, Magnesium Chloride, Glycerin, PEG/PPG-17/4 Dimethyl Ether, Sodium Hyaluronate, PEG-6, PEG-32, Hydroxyethyl Urea, Lauryl Betaine, Lactic Acid, Lavandula Angustifolia (Lavender) Oil, PEG-150, PPG-13-Decyltetradeceth-24, Triethanolamine, Sodium Citrate, Disodium EDTA, Citric Acid, Ammonium Lactate, Tocopherol, Phenoxyethanol, Sodium Benzoate. BIO-PERFORMANCE FULL EXPANSION SERUM: Water(Aqua/Eau), Dimethicone, Butylene Glycol, Dipropylene Glycol, Alcohol, Glycerin, Behenyl Alcohol, Triethylhexanoin, Silica, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Alpha-Glucan Oligosaccharide, Aminopropyl Dimethicone, Trifolium Pratense (Clover) Flower Extract (Trifolium Pratense Flower Extract), Lavandula Angustifolia (Lavender) Oil, Bupleurum Falcatum Rootextract, Batyl Alcohol, Hydrogenated Palm Oil, Behenic Acid, Elaeis Guineensis (Palm) Kernel Oil, PEG-60 Glyceryl Isostearate, PEG-10 Dimethicone, Elaeis Guineensis (Palm) Oil, Tocopherol, Sodium Metaphosphate, Potassium Hydroxide, Sodium Metabisulfite, Cinnamomum Cassia Bark Extract, Citric Acid, Phenoxyethanol.

  • Shipping & Returns

    • Our Normal Gift Boxing is not available for these items.
    • California and Minnesota customers call 1-800-777-0000 for Free Shipping information.
    You have 30 days to return most Bloomingdale's purchases. The Final Offer items are Final Sale and cannot be returned. For complete details, see our Shipping and Returns policies.

Ratings & Reviews

Here's what customers think
  • Customers report skin feels softer, smoother, and more hydrated.
  • Many reviewers experienced a reduction in the appearance of fine lines and wrinkles.
  • Customers noticed improved skin firmness, plumpness, and a more radiant complexion.
  • The serums are described as lightweight, non-greasy, and absorb quickly into the skin.
  • Some customers found the bottle design awkward or prone to tipping.
AI-generated summary from 1,236 customers reviews.

4.6/5

1,243 star ratings & reviews

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1,243 reviewssorted by Newest

KATE
15 days ago
Incentivized review
SUBMITTED AS A SWEEPSTAKES ENTRYYes

Love It

Jennifer Chan is a fantastic sales associate, and I really appreciate her recommending Bio-Performance Full Expansion Serum that I truly needed. After using the product for a few days, I can already tell that my face looks plumper and more refreshed. I am very happy with the results, and I will continue to use the product. Thank you so much Jennifer for your wonderful recommendation!

Recommends this product

Hideko
25 days ago
Incentivized review

Shiseido Skincare is the best -

Shiseido makes the best anti aging serums! I am very happy with the purchase! Over 40 plus years I have purchased Shiseido Skincare and Makeup at Macy's.

Customer review from macys.com

NC
1 month ago

The product is my third purchase since Dec 2025. The issue is the daytime use is expended / finishes way earlier than the nighttime use. It may be due to texture. Something needs to be done . All three purchases resulted in the same situation. I use the amount as directed. Thanks

Recommends this product

Customer review from macys.com

Chandra
2 months ago
Incentivized review

I swear by these two!

I can see the difference in my skin. I have people telling me I like 35. I just turned 51 last month.

Recommends this product

Customer review from Shiseido US

Andrea
3 months ago
Incentivized review

This filler is a fantastic product!

I absolutely love the morning and night filler. My skin looks amazing because of it.

Recommends this product

Customer review from Shiseido US

Karen
4 months ago
Incentivized review

Fantastic Fillers for Your Face

The skin Filler Serum keeps my face looking amazing. I have been using the filler since Shiseido came out with them.

Recommends this product

Customer review from Shiseido US

Ella
4 months ago

Buy

One of the best esp the blue!

Recommends this product

Customer review from Shiseido US

Monica
4 months ago

Not worth of money

Didnt see any improvement as advertised.

Customer review from Shiseido US